Bonnici Hanne, Bygum Anette
Odense Universitetshospital, Geriatrisk Afdeling G.
Ugeskr Laeger. 2007 Mar 26;169(13):1233-4.
Stevens-Johnson syndrome is an acute inflammatory and reactive disorder with skin and severe mucous membrane changes. Often patients have associated constitutional symptoms, including fever. The syndrome can be precipitated by infection or medication. We report a case of losartan-induced Stevens-Johnson syndrome associated with renal impairment in a geriatric patient.
史蒂文斯-约翰逊综合征是一种伴有皮肤和严重黏膜改变的急性炎症性反应性疾病。患者通常伴有全身性症状,包括发热。该综合征可由感染或药物诱发。我们报告一例老年患者因服用氯沙坦引发史蒂文斯-约翰逊综合征并伴有肾功能损害的病例。