Jo Min-Woo, Lee Sang-Il
Department of Preventive Medicine, College of Medicine, Dongguk University, Korea.
J Prev Med Public Health. 2007 Mar;40(2):169-76. doi: 10.3961/jpmph.2007.40.2.169.
This study was conducted to elicit quality weights for 42 EQ-5D health states with the time trade-off (TTO) method from the general population of South Korea.
We selected the same EQ-5D health states as those in the UK MVH study. The Korean version of EQ-5D questionnaire and TTO method were used for the valuation process. We interviewed 500 people as a representative sample of the general population in Seoul and Gyeonggi-do. The result was compared with those from UK, Japan, and USA by Spearman's rank correlation and t-test.
TTO values for 42 EQ-5D health states and 'unconscious' state were obtained from the general South Korean population. The best one was '11112' state and the worst one was 'unconscious' state. The states worse than death were '33323', '33333', and 'unconscious' states, which had negative TTO values. There was a strong correlation between TTO values of the EQ-5D health states and those of their corresponding states from UK, Japan, and USA (Spearman's correlation coefficient: 0.885, 0.882, and 0.944, respectively, p <0.001). However, absolute TTO values of most EQ-5D health states were significantly different from those of their corresponding states in other foreign studies (UK: 41/42, USA: 32/42, Japan: 15/17).
We found that the Korean general population TTO values for EQ-5D health states were different from those of other foreign studies, suggesting that a specific Korean valuation set should be developed and used for economic evaluation studies in South Korea.
本研究旨在采用时间权衡(TTO)方法,从韩国普通人群中获取42种EQ-5D健康状态的质量权重。
我们选取了与英国MVH研究相同的EQ-5D健康状态。评估过程中使用了EQ-5D问卷的韩语版本和TTO方法。我们采访了500人,作为首尔和京畿道普通人群的代表性样本。通过Spearman等级相关性分析和t检验,将结果与英国、日本和美国的结果进行比较。
从韩国普通人群中获得了42种EQ-5D健康状态和“无意识”状态的TTO值。最佳状态为“11112”,最差状态为“无意识”状态。比死亡更糟的状态为“33323”、“33333”和“无意识”状态,其TTO值为负。EQ-5D健康状态的TTO值与其在英国、日本和美国相应状态的TTO值之间存在很强的相关性(Spearman相关系数分别为0.885、0.882和0.944,p<0.001)。然而,大多数EQ-5D健康状态的绝对TTO值与其他国外研究中相应状态的绝对TTO值存在显著差异(英国:41/42,美国:32/42,日本:15/17)。
我们发现,韩国普通人群对EQ-5D健康状态的TTO值与其他国外研究不同,这表明应开发特定的韩国评估集,并用于韩国的经济评估研究。