Duda John E
Parkinson's Disease Research, Education and Clinical Center (PADRECC), Philadelphia VA Medical Center, Philadelphia, PA, USA.
CNS Spectr. 2007 Apr;12(4 Suppl 5):6-10. doi: 10.1017/s1092852900025955.
The syndrome now known as involuntary emotional expression disorder (IEED) is a condition characterized by uncontrollable episodes of laughing and/or crying. It has been known for more than a century, but confusing and conflicting terminology may have hampered the progress of physicians in recognizing this condition. IEED is associated with various neurological disorders and neurodegenerative diseases, including amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease and other dementias, and neurological injuries such as stroke and traumatic brain injury. It is hoped that better defined terminology for IEED may help in the future diagnosis of this debilitating condition, the establishment of accurate prevalence rates for IEED in the varying underlying conditions, and also in removing blame and stigma from sufferers by providing reassurance about the nature of their condition.
现在被称为情感失控表达障碍(IEED)的综合征是一种以无法控制的笑和/或哭发作发特征的病症。它已为人所知超过一个世纪,但混乱且相互矛盾的术语可能阻碍了医生认识这种病症的进程。IEED与各种神经系统疾病和神经退行性疾病相关,包括肌萎缩侧索硬化症、多发性硬化症、帕金森病、阿尔茨海默病和其他痴呆症,以及中风和创伤性脑损伤等神经损伤。人们希望,对IEED更明确的术语定义可能有助于未来对这种使人衰弱的病症进行诊断,确定IEED在不同潜在病症中的准确患病率,并且通过让患者放心其病症的性质来消除对患者的指责和污名。