Aksoy Umit, Tuncay Sema
Dokuz Eylül Universitesi Tip Fakültesi, Parazitoloji Anabilim Dali, Izmir.
Mikrobiyol Bul. 2007 Jan;41(1):127-31.
The intestinal protozoa have been increasingly identified in immunocompromised patients. In this study, stool samples of 554 patients [288 male, 266 female; 11 (2%) of them were immunocompromised] with diarrhea were examined between June 2004 and June 2005 in the Parasitology Laboratory of Dokuz Eylul University Hospital, Izmir, Turkey, in order to investigate the prevalence of intestinal coccidia. After formalin-ethyl acetate sedimentation procedure, the samples were examined by both native lugol and Kinyoun acid-fast staining methods for the detection of Cryptosporidium, Cyclospora and Isospora spp. As a result, Isospora belli oocysts were detected in the stool samples of two patients (0.4%) of which one was HIV positive and the other had experienced liver transplantation. Seven (1.3%) and two (0.4%) of the immunocompetent subjects were found positive for Cryptosporidium spp. and for Cyclospora cayetanensis, respectively. In conclusion, Isospora is one of the important protozoa which should be taken into consideration by clinicians in the immunocompromised patients with diarrhea.
免疫功能低下患者体内越来越多地发现肠道原生动物。在本研究中,2004年6月至2005年6月期间,在土耳其伊兹密尔多库兹艾吕尔大学医院寄生虫学实验室,对554例腹泻患者[288例男性,266例女性;其中11例(2%)为免疫功能低下患者]的粪便样本进行检测,以调查肠道球虫的感染率。经过福尔马林 - 乙酸乙酯沉淀法处理后,采用自然卢戈氏碘液染色法和金扬抗酸染色法对样本进行检测,以检测隐孢子虫、环孢子虫和等孢子虫属。结果,在两名患者(0.4%)的粪便样本中检测到贝氏等孢子虫卵囊,其中一名为HIV阳性,另一名曾接受肝移植。免疫功能正常的受试者中,分别有7例(1.3%)和2例(0.4%)隐孢子虫属和卡耶塔环孢子虫检测呈阳性。总之,等孢子虫是腹泻的免疫功能低下患者临床医生应考虑的重要原生动物之一。