Sato Shuzo, Irisawa Atsushi, Shio Kiori, Takagi Tadayuki, Ohira Hiromasa
Department of Internal Medicine II, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.
Fukushima J Med Sci. 2006 Dec;52(2):135-42.
A 70-year-old man with acute pancreatitis (acute exacerbation of chronic pancreatitis) was admitted to our department. Despite temporary improvement, the pancreatitis worsened on the 21st hospital day, forming a pancreatic pseudocyst, with infection in the cyst. After treatment with various antibiotics, a blood test on the 71st hospital day indicated improved inflammatory response despite continuing abdominal cramps. From the 75th hospital day, the patient developed purpura and arthralgia of the lower limbs, with melena and hematuria. Henoch-Schonlein purpura was diagnosed definitively by skin biopsy. Such a complication of acute pancreatitis with Henoch-Schönlein purpura is rare. This case also suggests that microvasculitis around the pancreas resulting from Henoch-Schonlein purpura might have prolonged the pancreatitis.
一名患有急性胰腺炎(慢性胰腺炎急性加重)的70岁男性入住我院。尽管病情暂时有所改善,但在住院第21天胰腺炎病情恶化,形成胰腺假性囊肿,囊肿内有感染。在使用多种抗生素治疗后,住院第71天的血液检查表明,尽管仍有腹部绞痛,但炎症反应有所改善。从住院第75天起,患者出现紫癜和下肢关节痛,并伴有黑便和血尿。通过皮肤活检确诊为过敏性紫癜。急性胰腺炎合并过敏性紫癜的这种并发症很罕见。该病例还提示,过敏性紫癜导致的胰腺周围微血管炎可能延长了胰腺炎的病程。