Satoh M, Mikuniya A, Mikami M, Higashiyama A, Sasaki N, Tahkahashi M, Fukushi K, Onodera K, Oike Y
Second Department of Internal Medicine, Hirosaki University School of Medicine.
Kokyu To Junkan. 1991 Mar;39(3):273-7.
A rare case of Schönlein-Henoch purpura with myocardial complications was reported. A 64-year-old man was admitted to our hospital for further examination of hematuria, associated with arthralgia, proteinuria, and previous episodes of anasarca and orthopnea. The examinations revealed moderate renal dysfunction due to mesangial proliferative glomerulonephritis secondary to Schönlein-Henoch purpura. In addition, the patient proved to have cardiac dilatation and dysfunction of the left ventricle. The histological examination of the right ventricular subendocardium sampled by myocardial biopsy showed myocardial damage, suggesting the invasion of microvasculitis in Schönlein-Henoch purpura to the peripheral coronary vessels. These findings indicate that myocardial damage induced in the patient may be one of the complications caused by Schönlein-Henoch purpura.
报告了一例罕见的伴有心肌并发症的过敏性紫癜。一名64岁男性因血尿进一步检查入院，伴有关节痛、蛋白尿，既往有全身性水肿和端坐呼吸发作史。检查发现，由于过敏性紫癜继发的系膜增生性肾小球肾炎导致中度肾功能不全。此外，患者被证实存在心脏扩张和左心室功能障碍。经心肌活检获取的右心室心内膜下组织学检查显示心肌损伤，提示过敏性紫癜中的微血管炎侵袭了外周冠状动脉血管。这些发现表明，该患者所出现的心肌损伤可能是过敏性紫癜引起的并发症之一。
