Dasgupta B, Hassan N
Essex University, and Department of Rheumatology, Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, Essex, UK.
Clin Exp Rheumatol. 2007 Jan-Feb;25(1 Suppl 44):S62-5.
This article reviews some of the recent work in epidemiology and pathology of giant cell arteritis (GCA), with particular regard to the immuno-histochemical findings in temporal artery biopsy (TAB) specimens. The diagnostic as well as prognostic role of biopsy histology is discussed. The role of novel imaging techniques e.g. duplex ultrasonography and FDG-PET scanning in diagnosis and staging of disease extent is reviewed. Existing evidence on the treatment is also discussed to propose guidelines on management of GCA.
本文综述了巨细胞动脉炎（GCA）流行病学和病理学方面的一些近期研究工作，尤其关注颞动脉活检（TAB）标本的免疫组织化学研究结果。讨论了活检组织学在诊断和预后方面的作用。还综述了新型成像技术，如双功超声和氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）扫描在疾病范围诊断和分期中的作用。此外，还讨论了现有治疗证据，以提出GCA管理指南。
