Dillon M J
Nephro-Urology Unit, Institute of Child Health, University College London, London, UK.
Clin Exp Rheumatol. 2007 Jan-Feb;25(1 Suppl 44):S66-8.
Recent developments in relation to Henoch-Schönlein purpura (HSP) include: a) a proposed new classification of childhood vasculitides including new classification criteria for HSP; b) the identification of various, potentially important, genetic polymorphisms in HSP that may be relevant in terms of predisposition to or protection from complications; c) evidence that prophylactic steroid at the onset of disease does not protect against renal or gastrointestinal complications but does seem to have beneficial effects in treating them.
与过敏性紫癜(HSP)相关的近期进展包括:a)提出了儿童血管炎的新分类,包括HSP的新分类标准;b)在HSP中鉴定出各种可能重要的基因多态性,这可能与易感性或预防并发症有关;c)有证据表明,疾病发作时使用预防性类固醇不能预防肾脏或胃肠道并发症,但似乎对治疗这些并发症有有益效果。