Spezio Michael L, Huang Po-Yin Samuel, Castelli Fulvia, Adolphs Ralph
Division of the Humanities and Social Sciences, California Institute of Technology, Pasadena, California 91125, USA.
J Neurosci. 2007 Apr 11;27(15):3994-7. doi: 10.1523/JNEUROSCI.3789-06.2007.
The role of the human amygdala in real social interactions remains essentially unknown, although studies in nonhuman primates and studies using photographs and video in humans have shown it to be critical for emotional processing and suggest its importance for social cognition. We show here that complete amygdala lesions result in a severe reduction in direct eye contact during conversations with real people, together with an abnormal increase in gaze to the mouth. These novel findings from real social interactions are consistent with an hypothesized role for the amygdala in autism and the approach taken here opens up new directions for quantifying social behavior in humans.
人类杏仁核在真实社交互动中的作用基本上仍不为人知，尽管对非人类灵长类动物的研究以及对人类使用照片和视频的研究表明，杏仁核对情绪处理至关重要，并暗示其对社会认知的重要性。我们在此表明，杏仁核完全损伤会导致在与真人对话时直接眼神接触严重减少，同时对嘴部的注视异常增加。这些来自真实社交互动的新发现与杏仁核在自闭症中的假定作用一致，并且这里采用的方法为量化人类社会行为开辟了新方向。
