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一名肝细胞癌患者的高钙血症性脑病。

Hypercalcemic encephalopathy in a patient with hepatocellular carcinoma.

作者信息

Tudela Pere, Soldevila Berta, Mòdol Josep Maria, Domènech Eugeni

机构信息

Unitat de Curta Estada, Emergency Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain.

出版信息

Dig Dis Sci. 2007 Nov;52(11):3296-7. doi: 10.1007/s10620-006-9159-4. Epub 2007 Apr 11.

DOI:10.1007/s10620-006-9159-4
PMID:17429730
Abstract

Cirrhotic patients with hepatocellular carcinoma (HCC) frequently develop hepatic encephalopathy. Metabolic etiology of encephalopathy is less often considered in these patients. Although paraneoplastic hypercalcemia may be associated with several malignant tumors, it has also been described in HCC [1-4], and may cause neurologic disturbances. We present a case of hypercalcemic encephalopathy in a patient with hepatic cirrhosis and underlying HCC in whom first diagnostic was hepatic encephalopathy.

摘要

患有肝细胞癌(HCC)的肝硬化患者经常会出现肝性脑病。在这些患者中,较少考虑脑病的代谢病因。虽然副肿瘤性高钙血症可能与几种恶性肿瘤有关,但在HCC中也有相关描述[1-4],并且可能导致神经功能障碍。我们报告一例肝硬化合并潜在HCC患者发生高钙血症性脑病的病例,该患者最初诊断为肝性脑病。

相似文献

1
Hypercalcemic encephalopathy in a patient with hepatocellular carcinoma.一名肝细胞癌患者的高钙血症性脑病。
Dig Dis Sci. 2007 Nov;52(11):3296-7. doi: 10.1007/s10620-006-9159-4. Epub 2007 Apr 11.
2
Hypercalcaemia secondary to hepatocellular carcinoma.
Ital J Gastroenterol Hepatol. 1999 Oct;31(7):604-6.
3
Subcutaneous fat necrosis with hypercalcemia.皮下脂肪坏死伴高钙血症。
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Acute hyperammonemic encephalopathy in a non-cirrhotic patient with hepatocellular carcinoma reversed by arginine therapy.精氨酸治疗逆转非肝硬化肝细胞癌患者的急性高氨血症性脑病
J Pain Symptom Manage. 2014 Apr;47(4):e5-7. doi: 10.1016/j.jpainsymman.2014.01.002.
5
Administration of bisphosphonates for malignant hepatic tumor with hypercalcemia.
Hepatogastroenterology. 2012 Mar-Apr;59(114):444-7. doi: 10.5754/hge09326.
6
Hashimoto's encephalopathy in a ten-year-old girl.
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7
A Proposed Physiopathological Pathway to Hyperammonemic Encephalopathy in a Non-Cirrhotic Patient with Fibrolamellar Hepatocellular Carcinoma without Ornithine Transcarbamylase (OTC) Mutation.一名非肝硬化的纤维板层型肝细胞癌患者,无鸟氨酸转氨甲酰酶(OTC)突变,发生高氨血症性脑病的拟议病理生理途径。
Am J Case Rep. 2017 Mar 8;18:234-241. doi: 10.12659/ajcr.901682.
8
[Paraneoplastic hypercalcemias. Apropos of 2 neuro-psychic forms].
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9
Hepatocellular carcinoma with pyrexia: report of a case.伴有发热的肝细胞癌:一例报告
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[Hepatoma manifesting monoclonal gammapathy and hypercalcemia].
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引用本文的文献

1
Epidemiology and prognosis of paraneoplastic syndromes in hepatocellular carcinoma.肝细胞癌副肿瘤综合征的流行病学与预后
ISRN Oncol. 2013 Dec 11;2013:684026. doi: 10.1155/2013/684026. eCollection 2013.
2
Successful Treatment in a Case of Massive Hepatocellular Carcinoma with Paraneoplastic Syndrome.巨大肝细胞癌伴副肿瘤综合征一例的成功治疗
Case Rep Gastroenterol. 2009 Apr 25;3(1):105-110. doi: 10.1159/000213480.

本文引用的文献

1
Clinical practice. Hypercalcemia associated with cancer.临床实践。癌症相关的高钙血症。
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Severe hypercalcemia as an initial presenting manifestation of hepatocellular carcinoma.
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Hypercalcaemia secondary to hepatocellular carcinoma.
Ital J Gastroenterol Hepatol. 1999 Oct;31(7):604-6.
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Parathyroid hormone-related peptide as a possible cause of hypercalcemia in a hepatocellular carcinoma patient.
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