基于B5r基因的印度水牛痘病毒分离株与其他正痘病毒的序列分析
B5r gene based sequence analysis of Indian buffalopox virus isolates in relation to other orthopoxviruses.
作者信息
Singh R K, Balamurugan V, Hosamani M, DE U K, Chandra B M, Krishnappa M P G
机构信息
Indian Veterinary Research Institute (IVRI), Mukteswar, Nainital District, Uttaranchal, India.
出版信息
Acta Virol. 2007;51(1):47-50.
We determined complete nucleotide sequence of B5R gene homologue of Vaccinia virus (VACV) in five Buffalopox virus (BPXV) isolates of Indian origin. The obtained sequences were compared with themselves and with corresponding sequences of the other orthopoxviruses. Sequence analysis revealed 99.799.8% and 99.499.7% identities among the BPXV isolates for B5R gene at the nucleotide and amino acid levels, respectively. Sequence identities of B5R gene between BPXV and VACV isolates (98.199.7%) or other orthopoxviruses (95.699.2%) showed highly conserved nature of this protein and a closer relationship of BPXV isolates to VACV than to other orthopoxviruses.
我们测定了源自印度的五株水牛痘病毒（BPXV）分离株中痘苗病毒（VACV）B5R基因同源物的完整核苷酸序列。将获得的序列相互之间以及与其他正痘病毒的相应序列进行了比较。序列分析显示，BPXV分离株之间B5R基因在核苷酸水平和氨基酸水平的同一性分别为99.7% - 99.8%和99.4% - 99.7%。BPXV与VACV分离株（98.1% - 99.7%）或其他正痘病毒（95.6% - 99.2%）之间B5R基因的序列同一性表明该蛋白具有高度保守性，且BPXV分离株与VACV的关系比与其他正痘病毒的关系更密切。
Zotero 插件