Adams G G, Stevenson K E, Kirkness C M, Steele A D, Rice N S
Professorial Unit, Moorfields Eye Hospital, London.
Eye (Lond). 1991;5 ( Pt 4):412-9. doi: 10.1038/eye.1991.66.
One hundred and forty acute corneal rejection episodes in 94 patients were studied retrospectively. Sixteen episodes in 15 eyes were associated with raised intraocular pressure (IOP) on admission, three of whom had had previously elevated IOP. At six weeks, six (37.5%) still required hypotensive therapy. Five eyes with raised IOP at rejection had lost vision at six weeks. Five of the six eyes with graft failure at review had raised IOP either pre-graft, at rejection or at follow-up. Eyes grafted for herpes simplex keratitis with hypertensive rejection episodes had a higher mean admission IOP, with a more short-lived rise than other eyes.
对94例患者的140次急性角膜排斥反应发作进行了回顾性研究。15只眼中的16次发作与入院时眼压升高（IOP）有关，其中3例既往眼压就已升高。六周时，6例（37.5%）仍需要降压治疗。排斥反应时眼压升高的5只眼在六周时视力丧失。复查时移植失败的6只眼中，有5只在移植前、排斥反应时或随访时眼压升高。因单纯疱疹性角膜炎接受移植且发生高血压性排斥反应的眼平均入院眼压较高，眼压升高持续时间比其他眼更短。
