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骨折与骨质疏松门诊:1年随访结果及3个月依从性

The fracture and osteoporosis clinic: 1-year results and 3-month compliance.

作者信息

Blonk Marion C, Erdtsieck Ronald J, Wernekinck Marian G A, Schoon Erik J

机构信息

Department of Internal Medicine, Catharina Hospital Eindhoven, P.O. Box 1350, 5602 ZA Eindhoven, The Netherlands.

出版信息

Bone. 2007 Jun;40(6):1643-9. doi: 10.1016/j.bone.2007.01.023. Epub 2007 Mar 1.

Abstract

INTRODUCTION

A Fracture and Osteoporosis (F&O) clinic started in two major general hospitals in the South of the Netherlands on April 1st 2004. Its objectives were to perform easy and complete assessment of female and male patients aged 50 years and over, initially treated for a low-energy trauma fracture, and to evaluate its effectiveness for early diagnosis and treatment of osteoporosis.

METHODS

All eligible patients were selected from the digital X-ray system of the Emergency Department. DXA-scans and, if indicated, spinal radiographs were made. If osteoporosis was diagnosed, the F&O nurse explained the treatment strategy. Treatment advice was sent to the general practitioner (GP), who prescribed medication and provided further support. After 3 months, all osteoporosis patients received a compliance and side effects follow-up questionnaire.

RESULTS

Up to June 1st 2005, 1058 patients followed the diagnostic procedure; 584 patients did not. Three times more women (804) than men (254) suffered a fracture. Osteoporosis occurred 10% more often in women. Overall, 37.1% had osteoporosis, based on DXA-scan only, and 39.6% when spinal radiographs were added. Spinal radiographs of the thoracic and or lumbar spine were made in 166 patients, radiographs of the thorax in 114 patients. Overall, fractures of the wrist were most common, with fractures of the hand occurring most frequently in men (20.0%). All fracture sites, except foot and clavicula, were associated with a higher frequency of osteoporosis than in the Dutch population. The response rate to the 3-month compliance questionnaire was 73% increasing to 96% after telephone contact. 86% visited their GP; 11% did not because they already received anti-osteoporotic medication prior to the fracture. Bisphosphonates were prescribed to 84% and discontinued by 7%. 13% reported side effects of bisphosphonates. Only half of the patients received the recommended calcium supplementation.

CONCLUSIONS

The F&O clinic with its digital X-ray system facilitated easy, complete identification of fracture patients and early treatment of osteoporosis, which was frequently diagnosed. Self-reported compliance was high.

摘要

引言

2004年4月1日,荷兰南部的两家大型综合医院开设了骨折与骨质疏松症(F&O)门诊。其目标是对50岁及以上、最初因低能量创伤性骨折接受治疗的女性和男性患者进行简便且全面的评估,并评估其对骨质疏松症早期诊断和治疗的有效性。

方法

所有符合条件的患者均从急诊科的数字X射线系统中选取。进行双能X线吸收测定扫描(DXA扫描),并在必要时拍摄脊柱X光片。如果诊断出骨质疏松症,F&O门诊护士会解释治疗策略。治疗建议会发送给全科医生(GP),由其开药并提供进一步的支持。3个月后,所有骨质疏松症患者都会收到一份关于依从性和副作用的随访问卷。

结果

截至2005年6月1日,1058名患者接受了诊断程序;584名患者未接受。骨折的女性患者(804名)是男性患者(254名)的三倍。女性患骨质疏松症的几率比男性高10%。总体而言,仅基于DXA扫描,37.1%的患者患有骨质疏松症;若加上脊柱X光片,这一比例为39.6%。166名患者拍摄了胸腰椎的脊柱X光片,114名患者拍摄了胸部X光片。总体而言,手腕骨折最为常见,手部骨折在男性中最为频发(20.0%)。除足部和锁骨外,所有骨折部位的骨质疏松症发病率均高于荷兰人群。3个月依从性问卷的回复率为73%,经电话联系后升至96%。86%的患者去看了全科医生;11%的患者未去,因为他们在骨折前已接受抗骨质疏松药物治疗。84%的患者被开了双膦酸盐药物,7%的患者停药。13%的患者报告了双膦酸盐药物的副作用。只有一半的患者接受了推荐的钙补充剂。

结论

配备数字X射线系统的F&O门诊便于对骨折患者进行简便、全面的识别以及对经常被诊断出的骨质疏松症进行早期治疗。自我报告的依从性较高。

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