Dolk H
Eurocat (European Registration of Congenital Anomalies), Department of Epidemiology, Catholic University of Louvain, Brussels, Belgium.
Dev Med Child Neurol. 1991 Nov;33(11):974-83. doi: 10.1111/j.1469-8749.1991.tb14813.x.
Of 41 term infants surviving to seven years of age with head circumferences (HC) - 3 SD, 21 were mentally retarded (IQ less than or equal to 70) at seven years. HC - 2 SD was associated with mental retardation in 11 per cent of children. Socio-economic status did not affect mental outcome of children with HC - 3 SD, but higher socio-economic level was associated with better outcome for those with HC - 2 SD or who were normocephalic. Mental retardation in children with HC - 3 SD was more common in children with additional pathology. Of 25 children with no other pathology, one-quarter were mentally retarded at seven years; this was more common in children of normal birthweight. Disproportionate head-to-height ratio did not significantly affect outcome, although short stature was associated with less favourable outcome for those with HC - 2 SD or who were normocephalic.
在41名存活至7岁且头围（HC）低于-3标准差的足月儿中，21名在7岁时智力发育迟缓（智商小于或等于70）。HC低于-2标准差与11%的儿童智力发育迟缓相关。社会经济地位并未影响HC低于-3标准差儿童的智力发育结果，但较高的社会经济水平与HC低于-2标准差或头围正常儿童的更好结果相关。HC低于-3标准差的儿童中，智力发育迟缓在伴有其他病变的儿童中更为常见。在25名无其他病变的儿童中，四分之一在7岁时智力发育迟缓；这在出生体重正常的儿童中更为常见。头高比例失调对结果没有显著影响，尽管身材矮小与HC低于-2标准差或头围正常儿童的不太有利结果相关。
