Kipnis S L, Iakunin Iu A, Sysoeva I M, Trefilova E V, Abrosimova N A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1975;75(10):1470-5.
The report contains some results of clinical, biochemical and EEG studies convened in 24 children with convulsive attacks and in 34 children with organic lesions of the CNS and epileptiform syndromes. The authors point out to the important role of the diencephalic area in the pathogenesis of convulsive syndromes. Changes in the glucocortical functions of the adrenal system during the period of convulsive attacks are related to a disturbed regulation in the hypothalamo-hypophysar structure. The processes of readaptation are more disturbed in patients with organic lesions of the CNS in frequent attacks. The results of such studies speak of certain indications to hormone therapy in repeated convulsions in children, especially if the convulsions have an epileptiform character and occur in patients with organic lesions of the CNS.
该报告包含了对24名有惊厥发作的儿童以及34名患有中枢神经系统器质性病变和癫痫样综合征的儿童进行的临床、生化和脑电图研究的一些结果。作者指出间脑区域在惊厥综合征发病机制中的重要作用。惊厥发作期间肾上腺系统糖皮质功能的变化与下丘脑 - 垂体结构调节紊乱有关。中枢神经系统有器质性病变且频繁发作的患者再适应过程受到的干扰更大。此类研究结果表明，对于儿童反复惊厥，尤其是惊厥具有癫痫样特征且发生在中枢神经系统有器质性病变的患者中，激素治疗有一定指征。
