O'Connell R A, Sireci S N, Fastov M E, Cueva J E, Luck D, Nathanson M R, Van Heertum R L
Department of Psychiatry, St. Vincent's Hospital, New York, NY.
Gen Hosp Psychiatry. 1991 Sep;13(5):305-12. doi: 10.1016/0163-8343(91)90034-t.
Cerebral single photon emission computed tomography (SPECT), a method of functional brain imaging, measures cerebral blood flow and metabolism. This paper describes the imaging procedure and several cases where cerebral SPECT was of use in the differential diagnosis of medically ill patients who also presented with psychopathology. SPECT patterns in cerebrovascular disease, dementia, focal epilepsy, and AIDS are at present the best described and seem to be the most specific. Often changes in regional cerebral blood flow are seen before structural changes become apparent on CT or MRI. Cerebral SPECT can add valuable diagnostic information in assessing psychopathology in the medically ill and can often lead to changes in treatment.
脑单光子发射计算机断层扫描（SPECT）是一种功能性脑成像方法，可测量脑血流量和代谢。本文描述了成像过程以及脑SPECT在患有精神病理学症状的内科疾病患者鉴别诊断中的几个应用案例。目前，脑血管疾病、痴呆、局灶性癫痫和艾滋病中的SPECT模式描述得最为完善，似乎也最具特异性。在CT或MRI上结构变化显现之前，往往就能观察到局部脑血流量的变化。脑SPECT在评估内科疾病患者的精神病理学方面可提供有价值的诊断信息，且常常能导致治疗方案的改变。
