Young Graeme, Riley Colleen M, Chalmers Robin L, Hunt Chris
Visioncare Research Ltd., Farnham, Surrey, United Kingdom.
Optom Vis Sci. 2007 Apr;84(4):302-8. doi: 10.1097/OPX.0b013e318042af0c.
The purpose of this analysis was to measure the proportion of soft contact lens wearers who wear lenses in challenging environments and to evaluate their resulting comfort in those conditions. A second objective was to determine whether refitting with silicone hydrogel lenses affects lens comfort among subjects who wear lenses in these environments.
Baseline data were collected from 496 hydrogel soft lens wearers on the frequency of use of contact lenses and the associated comfort in 12 challenging environments. Subjects were then refit into second generation silicone hydrogel lenses: senofilcon A (n = 228), galyfilcon A (n = 132), or lotrafilcon B (n = 136). Comfort responses were compared for subjects who "always" or "frequently" used lenses in the queried environments after 2 weeks of silicone hydrogel daily lens wear.
More than 80% of subjects used habitual lenses "always" or "frequently" while reading, sitting in an air-conditioned or heated car, using a computer and while driving at night. Less than 40% used lenses "always" or "frequently" while riding in an airplane, at high altitudes, or while napping or sleeping. The least comfortable environments were in dusty, polluted or smoky environments (30% comfortable), and the most comfortable were while reading and using a computer. After 2 weeks use of senofilcon A and galyfilcon A lenses, comfort in all environments improved significantly (Wilcoxon signed rank) except for using a computer with galyfilcon A. After 2 weeks with lotrafilcon B lenses, there was improved comfort while using lenses in all environments except driving at night, using a computer and sitting in an air-conditioned or heated car (p < 0.04, Wilcoxon signed rank).
Daily wear contact lens wearers limit use of lenses during air travel or while napping. Use of daily wear silicone hydrogel lenses improved comfort significantly in most environments, allowing subjects to wear them in challenging environments.
本分析的目的是测量在具有挑战性环境中佩戴软性隐形眼镜的佩戴者比例，并评估他们在这些条件下的舒适度。第二个目标是确定改用硅水凝胶镜片是否会影响在这些环境中佩戴镜片的受试者的镜片舒适度。
收集了496名水凝胶软性镜片佩戴者的基线数据，内容包括隐形眼镜的使用频率以及在12种具有挑战性环境中的相关舒适度。然后，受试者改用第二代硅水凝胶镜片：senofilcon A（n = 228）、galyfilcon A（n = 132）或lotrafilcon B（n = 136）。在每天佩戴硅水凝胶镜片2周后，比较在询问环境中“总是”或“经常”使用镜片的受试者的舒适度反应。
超过80%的受试者在阅读、坐在空调或暖气车内、使用电脑以及夜间驾驶时“总是”或“经常”佩戴习惯性镜片。在乘坐飞机、处于高海拔地区或小睡或睡觉时，不到40%的受试者“总是”或“经常”佩戴镜片。最不舒适的环境是在多尘、污染或烟雾弥漫的环境中（30%感到舒适）最舒适的是在阅读和使用电脑时。在使用senofilcon A和galyfilcon A镜片2周后，除了使用galyfilcon A镜片使用电脑外，所有环境中的舒适度均有显著改善（Wilcoxon符号秩检验）。在使用lotrafilcon B镜片2周后，除了夜间驾驶、使用电脑和坐在空调或暖气车内外，在所有环境中使用镜片时的舒适度均有所提高（p < 0.04, Wilcoxon符号秩检验）。
日戴型隐形眼镜佩戴者在航空旅行或小睡期间会限制镜片的使用。在大多数环境中，使用日戴型硅水凝胶镜片可显著提高舒适度，使受试者能够在具有挑战性的环境中佩戴。
