Hafstrom Anna, Modig Fredrik, Karlberg Mikael, Fransson Per-Anders
Department of Otorhinolaryngology, University Hospital of Lund, Lund, Sweden.
Neuroreport. 2007 Mar 5;18(4):391-4. doi: 10.1097/WNR.0b013e328013e3eb.
Alcohol intoxication affects the vestibular system and balance control in many ways. We have investigated how acute, moderate (blood alcohol concentrations of 0.06+/-0.01%), and high (0.10+/-0.02%) alcohol intoxication affects the ability to perceive the visual horizontal and vertical and the visual field dependence measured with the rod and frame tests in 24 healthy participants. Alcohol ingestion impaired the ability to use gravitational vestibular cues when determining the visual vertical and horizontal, and caused increased visual field dependence. With conflicting gravitational and visual information, alcohol seems to promote a reweighting in balance control from a vestibular to a more visual dependency. Furthermore, the results indicate that alcohol intoxication at these levels start instigating a decompensation of minute subclinical vestibular asymmetries.
酒精中毒在许多方面影响前庭系统和平衡控制。我们研究了急性、中度（血液酒精浓度为0.06±0.01%）和高度（0.10±0.02%）酒精中毒如何影响24名健康参与者通过棒框试验测量的感知视觉水平和垂直方向以及视野依赖性的能力。摄入酒精会损害在确定视觉垂直和水平方向时利用重力前庭线索的能力，并导致视野依赖性增加。在重力和视觉信息相互冲突的情况下，酒精似乎会促使平衡控制从依赖前庭转向更多地依赖视觉。此外，结果表明，这些水平的酒精中毒开始引发微小的亚临床前庭不对称的失代偿。
