Miano C, Bosman C, Boldrini R, DonFrancesco A, Ceci A, Mancini S, Rosati D
Divisione di Ematologia Pediatrica, Ospedale Bambino Gesù, Roma, Italy.
Haematologica. 1991 May-Jun;76(3):240-2.
The authors report on a case of disseminated Langerhans' cell histiocytosis with a clinical presentation and a bone marrow simulating, at onset, an acute leukemia non lymphoid. A hepatic needle biopsy performed for the progressive enlargement of the liver oriented the diagnosis towards a Langerhans' cell histiocytosis. The morphological, immunohistochemical and ultrastructural study of these cells showed them to be undetermined, i.e. Langerhans' cell precursors.
作者报告了一例播散性朗格汉斯细胞组织细胞增多症，其临床表现及骨髓情况在疾病初期类似非淋巴细胞性急性白血病。因肝脏进行性肿大而进行的肝穿刺活检使诊断指向朗格汉斯细胞组织细胞增多症。对这些细胞进行的形态学、免疫组织化学及超微结构研究显示它们尚未确定，即朗格汉斯细胞前体细胞。
