Dietz H P
Nepean Clinical School, University of Sydney, Nepean Hospital, Penrith, NSW, 2750, Australia.
Int Urogynecol J Pelvic Floor Dysfunct. 2007 Jun;18(6):665-9. doi: 10.1007/s00192-007-0376-y. Epub 2007 Apr 14.
It is assumed that pelvic organ descent and prolapse increase with age. Epidemiological studies support this assumption. We aimed to define the relationship between age and bladder neck descent (BND) in a retrospective observational study on 790 women referred for evaluation of pelvic floor disorders. Bladder neck descent, cystocele descent and urethral rotation were evaluated on maximal Valsalva manoeuvre, using trans-labial ultrasound. There was a weak negative correlation between bladder neck descent on Valsalva and age (r = -0.154, p < 0.001), which was absent in nulliparous women (n = 107) and stronger (r = -0.213, p < 0.001) in parous women (n = 683). This relationship was evident from the age of 50 years onwards and may be explained by increased tissue stiffness after menopause. The difference observed between parous and nulliparous women is intriguing and raises the issue of obstetric confounders such as historical changes in the likelihood of significant pelvic floor trauma.
一般认为,盆腔器官脱垂会随着年龄的增长而加重。流行病学研究支持这一假设。在一项针对790名因盆底功能障碍前来评估的女性的回顾性观察研究中,我们旨在明确年龄与膀胱颈下移(BND)之间的关系。使用经阴唇超声,在最大Valsalva动作时评估膀胱颈下移、膀胱膨出下移和尿道旋转情况。Valsalva动作时膀胱颈下移与年龄之间存在微弱的负相关(r = -0.154,p < 0.001),未生育女性(n = 107)中不存在这种相关性,而在已生育女性(n = 683)中相关性更强(r = -0.213,p < 0.001)。这种关系从50岁起就很明显,可能是由于绝经后组织硬度增加所致。已生育女性和未生育女性之间观察到的差异很有趣,并引发了诸如盆底严重创伤可能性的历史变化等产科混杂因素的问题。