[细菌核酮糖单磷酸途径与甲醛同化作用]
[Bacterial ribulose monophosphate pathway and formaldehyde assimilation].
作者信息
Song Zhong-bang, Chen Li-mei, Li Kun-zhi, Pan Zheng-Bo
机构信息
Biotechnology Research Center, Kunming University of Science and Technology, Kunming 650224, China.
出版信息
Wei Sheng Wu Xue Bao. 2007 Feb;47(1):168-72.
Ribulose monophosphate pathway (RuMP), which was originally found in methylotrophic bacteria, is now recognized as a metabolic pathway widespread in most bacteria and involved in formaldehyde assimilation and detoxification. 3-Hexulose-6-phosphate synthase (HPS) and 6-phospho-3-hexuloisomerase (PHI) are the key enzymes of this pathway. This review describes the physiological significance of RuMP pathway derived from a variety of bacteria, the organizations and expressional regulations of HPS and PHI genes and the perspectives for applications of the two genes.
核糖单磷酸途径（RuMP）最初是在甲基营养细菌中发现的，现在被认为是一种在大多数细菌中广泛存在的代谢途径，参与甲醛同化和解毒。6-磷酸-3-己酮糖合酶（HPS）和6-磷酸-3-己酮糖异构酶（PHI）是该途径的关键酶。本文综述了来自多种细菌的RuMP途径的生理意义、HPS和PHI基因的组织及表达调控，以及这两个基因的应用前景。
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