Funauchi Masanori, Yamagata Toshiaki, Sugiyama Masafumi, Ikoma Shin-ya, Sakaguchi Mika, Kinoshita Koji, Kawata Akira
Department of Nephrology and Rheumatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama 589-8511, Japan.
Mod Rheumatol. 2007;17(2):153-5. doi: 10.1007/s10165-006-0550-y. Epub 2007 Apr 20.
A case of antiphospholipid antibody syndrome (APS) is presented, which manifested 5 years after onset of basal cell carcinoma (BCC). There were multiple collateral veins due to portal vein thrombosis. Because immunological abnormalities including anti-cardiolipin beta(2) glycoprotein-I antibody improved after surgical resection of BCC, it is likely that APS had occurred as a paraneoplastic syndrome with BCC. This case suggests that it is necessary to investigate the presence of APS when BCC is complicated by some coagulopathies.
本文报告1例抗磷脂抗体综合征（APS），其在基底细胞癌（BCC）发病5年后出现。因门静脉血栓形成出现多条侧支静脉。由于包括抗心磷脂β2糖蛋白-I抗体在内的免疫异常在BCC手术切除后得到改善，所以APS很可能是作为BCC的副肿瘤综合征发生的。该病例提示，当BCC合并某些凝血障碍时，有必要调查APS的存在情况。
