我们是否应该继续对RhD阳性女性进行妊娠晚期非典型抗体检测？
Should we continue screening rhesus D positive women for the development of atypical antibodies in late pregnancy?
作者信息
Adeniji A A, Fuller I, Dale T, Lindow S W
机构信息
Hull and East Yorkshire Hospitals, Hull Royal Infirmary, Hull, UK.
出版信息
J Matern Fetal Neonatal Med. 2007 Jan;20(1):59-61. doi: 10.1080/14767050601123317.
OBJECTIVE
The purpose of this study was to calculate the incidence of the new development of atypical antibodies (other than anti-rhesus D) in women attending for antenatal care, and to assess the clinical impact and cost-effectiveness of a second test to detect these antibodies.
METHOD
A three-year retrospective analysis was undertaken to calculate the number of rhesus positive women who developed new antibodies in the last trimester of pregnancy.
RESULTS
Of 13,143 rhesus positive women, 20 (0.15%) developed new antibodies; fetal outcome was not compromised in any of these cases.
CONCLUSION
Repeat testing in late pregnancy would appear an unnecessary expense in our population.
目的
本研究的目的是计算接受产前护理的女性中非典型抗体（抗恒河猴D以外的抗体）新出现的发生率，并评估进行第二次检测以检测这些抗体的临床影响和成本效益。
方法
进行了一项为期三年的回顾性分析，以计算在妊娠晚期产生新抗体的恒河猴阳性女性的数量。
结果
在13143名恒河猴阳性女性中，有20名（0.15%）产生了新抗体；在这些病例中，胎儿结局均未受到影响。
结论
在我们的人群中，妊娠晚期重复检测似乎是一项不必要的费用。
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