Reeves Jonathan T
Department of Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT 06877, USA.
Org Lett. 2007 May 10;9(10):1879-81. doi: 10.1021/ol070341i. Epub 2007 Apr 18.
A short and efficient total synthesis of the tripyrrole alkaloid butylcycloheptylprodigiosin is described. Key to the brevity of the approach is a two-step synthesis of macrocyclic formylpyrrole 4 from cyclononenone 6.