匈牙利家族性多发性硬化症的流行病学

Epidemiology of familial multiple sclerosis in Hungary.

作者信息

Fricska-Nagy Z, Bencsik K, Rajda C, Füvesi J, Honti V, Csépány T, Dobos E, Mátyás K, Rózsa C, Komoly S, Vécsei L

机构信息

Department of Neurology, Albert Szent-Gyögyi Medical and Pharmaceutical Centre, University of Szeged, Hungary.

出版信息

Mult Scler. 2007 Mar;13(2):260-1. doi: 10.1177/1352458506070767. Epub 2007 Jan 29.

DOI:10.1177/1352458506070767

PMID:17439894

Abstract

The prevalence of familial aggregation of multiple sclerosis (MS) is estimated between 5 and 10%. Studies emphasize the effect of genetic factors over the environment of the patients in the development of the disease. We investigated familial accumulation of MS in the cases of 1500 patients in five Hungarian MS centers. According to our data, the risk of familial MS in Hungary is lower than in other countries for which literature data are accessible. The literature does not contain any data for the prevalence of familial MS in Hungary and middle-eastern Europe.

摘要

多发性硬化症（MS）的家族聚集患病率估计在5%至10%之间。研究强调了遗传因素在该疾病发展过程中对患者所处环境的影响。我们在匈牙利的五个多发性硬化症中心对1500例患者进行了MS家族聚集情况的调查。根据我们的数据，匈牙利家族性MS的风险低于其他有文献数据可查的国家。文献中没有关于匈牙利和中东欧家族性MS患病率的任何数据。