Fow Jennifer, Grossman Sheila
Yale University School of Nursing, New Haven, Connecticut, USA.
Gastroenterol Nurs. 2007 Mar-Apr;30(2):93-8; quiz 98-100. doi: 10.1097/01.SGA.0000267927.77545.bd.
In Crohn disease, a vigorous inflammatory cascade is caused by the overactivation of helper T-cells in the gastrointestinal system. The results of this inflammation manifest themselves as the symptoms of Crohn disease. This article describes the pathophysiology of Crohn disease as well as multiple pharmacologic and nonpharmacologic interventions that may assist patients with Crohn disease in preventing exacerbations and maintaining longer remissions.
在克罗恩病中,胃肠道系统中辅助性T细胞的过度激活会引发强烈的炎症级联反应。这种炎症的结果表现为克罗恩病的症状。本文描述了克罗恩病的病理生理学,以及多种可能帮助克罗恩病患者预防病情加重和维持更长缓解期的药物和非药物干预措施。