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使用同种异体脱细胞真皮基质进行一期乳头再造以改善乳头长期突出度。

Use of AlloDerm in primary nipple reconstruction to improve long-term nipple projection.

作者信息

Garramone Charles E, Lam Benjamin

机构信息

Philadelphia, Pa. From the Department of Plastic and Reconstructive Surgery, Philadelphia College of Osteopathic Medicine.

出版信息

Plast Reconstr Surg. 2007 May;119(6):1663-1668. doi: 10.1097/01.prs.0000258831.38615.80.

Abstract

BACKGROUND

The objective of this study was to demonstrate the use of the authors' technique to improve long-term maintenance of nipple projection by using AlloDerm (LifeCell Corp., Branchburg, N.J.) as a central core in nipple reconstruction.

METHODS

The nipple reconstruction technique involved the use of a modified star dermal flap pattern measuring 5 cm in length and 1.0 to 1.5 cm in width, depending on the amount of desired projection to match the opposite nipple. Then, a 1.5 x 4.5-cm piece of AlloDerm was placed into the core of the newly reconstructed nipple and sutured closed. After the incisions were closed, an ocular eye bubble protector was used to prevent compressive forces on the newly reconstructed nipple, and strict postoperative use of this protector was maintained for 6 weeks.

RESULTS

A total of 30 nipple reconstructions were performed [14 transverse rectus abdominis musculocutaneous (TRAM) flaps and 16 tissue-expanded breast mounds]. Caliper measurements of nipple projection were recorded at the time of surgery and at 3, 6, and 12 months postoperatively. Twelve-month average maintenance of nipple projection was 56 percent for the TRAM flap group and 47 percent for the tissue-expanded group. There were no infections or associated complications.

CONCLUSIONS

The authors' results demonstrate that the use of a modified star dermal flap pattern with the placement of an AlloDerm graft core is a safe, easily performed, and reproducible technique for improving the long-term maintenance of projection in reconstructed nipples.

摘要

背景

本研究的目的是演示作者使用AlloDerm(LifeCell公司,新泽西州布兰奇堡)作为乳头重建的中心核心来改善乳头突出长期维持效果的技术。

方法

乳头重建技术包括使用改良的星形真皮瓣模式,其长度为5厘米,宽度为1.0至1.5厘米,具体取决于与对侧乳头匹配所需的突出量。然后,将一块1.5×4.5厘米的AlloDerm放入新重建乳头的核心并缝合关闭。切口闭合后,使用眼部气泡保护器防止对新重建乳头施加压力,并在术后严格使用该保护器6周。

结果

共进行了30例乳头重建手术[14例腹直肌肌皮瓣(TRAM)和16例组织扩张乳房]。在手术时以及术后3、6和12个月记录乳头突出的卡尺测量值。TRAM瓣组乳头突出的12个月平均维持率为56%,组织扩张组为47%。没有感染或相关并发症。

结论

作者的结果表明,使用带有AlloDerm移植核心的改良星形真皮瓣模式是一种安全、易于实施且可重复的技术,可改善重建乳头突出的长期维持效果。

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