探寻宝藏：T-bet的故事
Trawling for treasure: tales of T-bet.
作者信息
Glimcher Laurie H
机构信息
Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
出版信息
Nat Immunol. 2007 May;8(5):448-50. doi: 10.1038/ni0507-448.
PMID:17440449
Abstract
Discovering the transcription factors that direct lineage commitment in the T helper cell was a formidable task. Laurie Glimcher describes how she and Susanne Szabo hunted down T-bet, a transcription factor that is a 'master regulator' of commitment to the T helper type 1 lineage.
摘要
发现指导T辅助细胞谱系定向分化的转录因子是一项艰巨的任务。劳里·格林切尔描述了她和苏珊娜·萨博是如何找到T-bet的，T-bet是一种转录因子，是T辅助1型细胞谱系定向分化的“主调控因子”。
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