Bigalke Boris, Klingel Karin, May Andreas E, Kandolf Reinhard, Gawaz Meinrad Gawaz
Medizinische Klinik III, University Hospital of Tübingen, Tübingen, Germany.
Can J Cardiol. 2007 Apr;23(5):393-5. doi: 10.1016/s0828-282x(07)70775-4.
A 67-year-old woman who presented with acute chest pain is reported. Three days before admission, she suffered from a flu-like infection. Coronary angiography showed no coronary stenosis. Ventriculography showed moderately reduced left ventricular function characterized by the so-called 'apical ballooning'. Endomyocardial biopsies and polymerase chain reaction analysis of the plasma revealed an acute infection with human herpesvirus 6 subtype A. Histological and immunohistochemical analyses revealed myocarditis with areas of interstitial macrophages and fibrosis. The present case report links, for the first time, myocarditis with a human herpesvirus 6 subtype A infection and the appearance of apical ballooning.
报道了一名67岁出现急性胸痛的女性患者。入院前三天，她患有类似流感的感染。冠状动脉造影显示无冠状动脉狭窄。心室造影显示左心室功能中度降低，其特征为所谓的“心尖气球样变”。心内膜活检和血浆聚合酶链反应分析显示为人类疱疹病毒6型A亚型急性感染。组织学和免疫组化分析显示为心肌炎，伴有间质巨噬细胞和纤维化区域。本病例报告首次将心肌炎与人类疱疹病毒6型A亚型感染及心尖气球样变的出现联系起来。
