Rojas-Hijazo Beatriz, Lezaun Apolinar, Hausen Bjoern M, Segura Nieves, Mar Garcés M, Colás Carlos
Department of Allergology, Clinico Universitario Hospital, Zaragoza, Spain.
Contact Dermatitis. 2007 May;56(5):274-7. doi: 10.1111/j.1600-0536.2007.01095.x.
Exotic wood species are used in the manufacture of furniture, musical instruments, tool handles, and other wooden items. Exposure to sawdust of the wood can produce dermatitis on exposed areas in woodworkers. We studied 7 patients, gaitas constructors who used caviuna wood to make their instruments. They developed dermatitis on exposed areas hours after they had begun to work with caviuna. We performed patch tests using the European standard series, caviuna sawdust sample, and a series of dalbergiones. 15 controls were performed. Two caviuna samples provided by a patient were analysed by thin-layer chromatography (TLC). Patch test with caviuna sawdust yielded positive reactions in all patients. 5 of the 7 sufferers reacted strongly to obtusaquinine and (R)-4-methoxydalbergione deriving from Dalbergia retusa, but also to sensitizers present in other rosewoods. Patch tests with R-3,4-dimethoxydalbergione deriving from Machaerium scleroxylum remained negative in the patients, as well as in control subjects. The TLC analysis of the samples showed that the woods could have been M. scleroxylum, D. cearensis or D. frustescens, but not D. retusa. In our patients, airborne contact dermatitis was caused by exposure to caviuna sawdust. The patients must have been in contact with different Dalbergia species and especially with D. retusa.
外来木材品种被用于制造家具、乐器、工具手柄及其他木制物品。木工接触木材的锯末会在暴露部位引发皮炎。我们研究了7名用卡维纳木制作乐器的 gaitas 制作者。他们在开始使用卡维纳木工作数小时后，暴露部位出现了皮炎。我们使用欧洲标准系列、卡维纳锯末样本及一系列黄檀属化合物进行了斑贴试验。进行了15次对照试验。对一名患者提供的两份卡维纳样本进行了薄层色谱分析（TLC）。用卡维纳锯末进行的斑贴试验在所有患者中均产生了阳性反应。7名患者中有5名对钝叶黄檀中的 obtusaquinine 和（R）-4-甲氧基黄檀属化合物以及其他红木中的致敏剂有强烈反应。用硬荚豆属植物的 R-3,4-二甲氧基黄檀属化合物进行的斑贴试验在患者及对照受试者中均呈阴性。样本的TLC分析表明，这些木材可能是硬荚豆属植物、塞阿拉黄檀或弗氏黄檀，但不是钝叶黄檀。在我们的患者中，空气传播性接触性皮炎是由接触卡维纳锯末引起的。患者肯定接触过不同的黄檀属物种，尤其是钝叶黄檀。
