Sechi GianPietro, Agnetti Virgilio, Galistu Paola, Murgia Bastianino, Marrosu Francesco, Puligheddu Monica, Conti Maurizio, Paulus Kai Stephan
Institute of Neurological Clinic, University of Sassari, Viale San Pietro, 10, I-07100 Sassari, Italy.
Parkinsonism Relat Disord. 2008;14(2):157-60. doi: 10.1016/j.parkreldis.2007.02.004. Epub 2007 Apr 17.
We report the first instance of restless legs syndrome (RLS) associated with periodic limb movements (PLM) and disruption of sleep architecture occurring in a patient following ischemic infarction in the right lenticulostriate region. Recently, a role for the basal ganglia-brainstem system in the control of motor behaviors and in the regulation of awake-sleep states has been proposed. The purported roles of these structures may be relevant in explaining the occurrence of the RLS in our patient. The discrete brain localization observed in this patient may be a clue to a better understanding of the pathophysiology of RLS and PLM.
我们报告了首例与周期性肢体运动（PLM）相关的不宁腿综合征（RLS），该患者在右侧豆状核纹状体区域发生缺血性梗死后出现睡眠结构紊乱。最近，有人提出基底神经节 - 脑干系统在控制运动行为和调节清醒 - 睡眠状态中起作用。这些结构的所谓作用可能与解释我们患者中RLS的发生有关。在该患者中观察到的离散脑定位可能是更好地理解RLS和PLM病理生理学的线索。
