胶质母细胞瘤中的甲基鸟嘌呤甲基转移酶检测：何时以及如何进行？ - Suppr

Suppr

超能文献

Methylguanine methyltransferase testing in glioblastoma: when and how?

作者信息

Stupp Roger, Hegi Monika E

出版信息

J Clin Oncol. 2007 Apr 20;25(12):1459-60. doi: 10.1200/JCO.2006.09.7139.

DOI:10.1200/JCO.2006.09.7139

PMID:17442986

Abstract

摘要

相似文献

Methylguanine methyltransferase testing in glioblastoma: when and how?

J Clin Oncol. 2007 Apr 20;25(12):1459-60. doi: 10.1200/JCO.2006.09.7139.

The fallacy of single-agent chemotherapy for cancer.

J Clin Oncol. 2007 Aug 10;25(23):3550; author reply 3550-1. doi: 10.1200/JCO.2007.12.3596.

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide.

J Clin Oncol. 2007 Apr 20;25(12):1470-5. doi: 10.1200/JCO.2006.07.4807.

Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide.

Jpn J Clin Oncol. 2007 Dec;37(12):897-906. doi: 10.1093/jjco/hym132. Epub 2007 Dec 21.

Mechanisms of disease: temozolomide and glioblastoma--look to the future.

Nat Clin Pract Oncol. 2008 Aug;5(8):476-86. doi: 10.1038/ncponc1155. Epub 2008 Jun 10.

[O6-methylguanine-DNA-methyltransferase (MGMT) expression in patients with glioblastoma multiforme].

Rev Med Chil. 2018 Jan;146(1):7-14. doi: 10.4067/s0034-98872018000100007.

[Temozolomide in patients with a glioblastoma multiforme: new developments].

Ned Tijdschr Geneeskd. 2005 Jun 18;149(25):1376-8.

Phenytoin may increase the efficacy of temozolomide by methylating DNA-repair enzyme, O6-methylguanine-DNA methyltransferase in patients with glioblastoma.

Med Hypotheses. 2005;65(4):819-20. doi: 10.1016/j.mehy.2005.04.007.

Immunohistochemical evaluation of O6 -methylguanine DNA methyltransferase (MGMT) expression in 117 cases of glioblastoma.

Neuropathology. 2014 Jun;34(3):268-76. doi: 10.1111/neup.12091. Epub 2014 Jan 7.

Treatment of brain tumors.

N Engl J Med. 2005 Jun 2;352(22):2350-3; author reply 2350-3.

引用本文的文献

Revisiting Temozolomide's role in solid tumors: Old is gold?

J Cancer. 2024 Apr 22;15(11):3254-3271. doi: 10.7150/jca.94109. eCollection 2024.

Quantitative analysis of promoter methylation in glioblastoma suggests nonlinear prognostic effect.

Neurooncol Adv. 2023 Sep 19;5(1):vdad115. doi: 10.1093/noajnl/vdad115. eCollection 2023 Jan-Dec.

A peptide & peptide nucleic acid synthesis technology for transporter molecules and theranostics--the SPPS.

Int J Med Sci. 2014 May 7;11(7):697-706. doi: 10.7150/ijms.8168. eCollection 2014.

Double-labelling immunohistochemistry for MGMT and a "cocktail" of non-tumourous elements is a reliable, quick and easy technique for inferring methylation status in glioblastomas and other primary brain tumours.

Acta Neuropathol Commun. 2013 Jun 10;1:22. doi: 10.1186/2051-5960-1-22.

DNA methylation of the p14ARF, RASSF1A and APC1A genes as an independent prognostic factor in colorectal cancer patients.

Int J Oncol. 2013 Jan;42(1):127-33. doi: 10.3892/ijo.2012.1682. Epub 2012 Oct 30.

BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1α stability and MGMT expression.

Cell Death Dis. 2012 Oct 18;3(10):e412. doi: 10.1038/cddis.2012.153.

O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems.

Biochim Biophys Acta. 2012 Aug;1826(1):71-82. doi: 10.1016/j.bbcan.2011.12.004. Epub 2012 Jan 8.

Tumour and serum MGMT promoter methylation and protein expression in glioblastoma patients.

Clin Transl Oncol. 2011 Sep;13(9):677-85. doi: 10.1007/s12094-011-0714-x.

O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.

BMC Cancer. 2011 Jan 26;11:35. doi: 10.1186/1471-2407-11-35.

Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerations.

Cancer Manag Res. 2009 Oct 30;1:137-50. doi: 10.2147/cmr.s5598.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验