Gould D J, Chudleigh J H, Moralejo D, Drey N
City University, School of Nursing and Midwifery, 24 Chiswell Street, London, UK EC1 4TY.
Cochrane Database Syst Rev. 2007 Apr 18(2):CD005186. doi: 10.1002/14651858.CD005186.pub2.
Health care-associated infection is a major cause of morbidity and mortality. Hand hygiene is regarded as an effective preventive measure.
To assess the short and longer-term success of strategies to improve hand hygiene compliance and to determine whether a sustained increase in hand hygiene compliance can reduce rates of health care-associated infection.
We conducted electronic searches of: the Cochrane Central Register of Controlled Trials; the Cochrane Effective Practice and Organisation of Care Group specialised register of trials; MEDLINE; PubMed; EMBASE; CINAHL; and the BNI. All databases were searched to July 2006; MEDLINE was searched from 1980, CINAHL from its inception, and the remainder from 1990 until July 2006.
Randomised controlled trials; controlled clinical trials; controlled before and after studies; and interrupted time series analyses meeting explicit entry and quality criteria used by the Cochrane Effective Practice and Organisation of Care Group. Studies reporting proxy indicators of hand hygiene compliance were considered. Studies to promote compliance with universal precautions were included providing data relating specifically to hand hygiene were presented separately.
Two reviewers independently extracted data and assessed data quality.
Two studies met the criteria for review. One was a randomised controlled trial. The other was a controlled before and after study. Both were poorly controlled. Statistically significant post-intervention increase in hand washing was reported in one study up to four months after the intervention. In the other there was no post-intervention increase in hand hygiene compliance.
AUTHORS' CONCLUSIONS: There is little robust evidence to inform the choice of interventions to improve hand hygiene. It appears that single interventions based on short, 'one off' teaching sessions are unlikely to be successful, even short-term. There is a need to undertake methodologically robust research to explore the effectiveness of soundly designed interventions to increase hand hygiene compliance.
医疗保健相关感染是发病和死亡的主要原因。手部卫生被视为一种有效的预防措施。
评估提高手部卫生依从性策略的短期和长期成效,并确定手部卫生依从性的持续提高是否能降低医疗保健相关感染率。
我们对以下数据库进行了电子检索:Cochrane对照试验中央注册库;Cochrane有效实践与护理组织小组专业试验注册库;MEDLINE;PubMed;EMBASE;CINAHL;以及BNI。所有数据库检索至2006年7月;MEDLINE从1980年开始检索,CINAHL从其创刊起检索,其余数据库从1990年至2006年7月进行检索。
随机对照试验;对照临床试验;前后对照研究;以及符合Cochrane有效实践与护理组织小组明确纳入标准和质量标准的中断时间序列分析。考虑报告手部卫生依从性替代指标的研究。纳入促进普遍预防措施依从性的研究,前提是单独提供与手部卫生具体相关的数据。
两名评价员独立提取数据并评估数据质量。
两项研究符合综述标准。一项是随机对照试验。另一项是前后对照研究。两项研究的对照都很差。一项研究报告称,干预后长达四个月洗手有统计学意义的增加。另一项研究中,干预后手部卫生依从性没有增加。
几乎没有有力证据可指导改善手部卫生干预措施的选择。基于短期“一次性”教学课程的单一干预措施似乎不太可能成功,即使是短期的。需要进行方法学上可靠的研究,以探索精心设计的干预措施提高手部卫生依从性的有效性。