Sgouros Spiros N, Vassiliadis Konstantinos, Bergele Christina, Vlachogiannakos Jiannis, Stefanidis Gerasimos, Mantides Apostolos
Department of Gastroenterology, Athens Naval and Veterans Hospital, Athens, Greece.
J Gastroenterol Hepatol. 2007 May;22(5):653-7. doi: 10.1111/j.1440-1746.2006.04368.x.
Distal esophageal (Schatzki's) ring is a frequent cause of dysphagia. Bougienage is generally effective but relapses are common. The aim of this study was to evaluate the safety and long-term efficacy of single-session graded esophageal dilation with Savary dilators, without fluoroscopic guidance, in outpatients who presented with Schatzki's ring.
The study was performed on 44 consecutive patients with symptomatic Schatzki's ring, detected endoscopically and/or radiologically. Graded esophageal dilation was performed as an outpatient procedure in a single session with Savary dilators, without fluoroscopic guidance. After appropriate assessment with esophageal manometry and 24 h ambulatory pHmetry, patients with documented gastroesophageal reflux disease (GERD) were treated with omeprazole continuously. All results, including clinical follow up and technical aspects of bougienage, were recorded prospectively. The necessity for re-dilation after documentation of the ring with endoscopy and/or radiology was considered as a relapse of the ring.
In four (9%) patients a second session was necessary to ensure complete symptom relief. Two (4.5%) patients developed post-dilation bacteremia and were managed with antibiotics as outpatients. Patients with (n = 14) or without (n = 30) GERD were comparable with respect to sex, age, body mass index, smoke and ethanol consumption, diameter of the esophageal lumen at the level of the ring, resting lower esophageal sphincter pressure, duration of dysphagia, need for taking antacids during the follow-up period, and duration of follow-up. There was no recurrence of the ring in patients with GERD during a mean follow-up period of 43.8 +/- 9.3 months (range 27-62 months); however, in patients without GERD, during a mean follow-up period of 40.6 +/- 12.2 months (range 10-58 months), 32% of patients relapsed after a mean 19.9 +/- 10.6 months (P = 0.04).
Single-session graded esophageal dilation with large caliber Savary dilators without fluoroscopic guidance can be safely used for the symptomatic relief in patients with lower esophageal (Schatzki's) rings. GERD should be treated if present in order to prevent a symptomatic recurrence of the ring.
食管远端(沙茨基氏)环是吞咽困难的常见原因。探条扩张术通常有效,但复发很常见。本研究的目的是评估在无荧光透视引导下,使用萨瓦里扩张器对门诊沙茨基氏环患者进行单疗程分级食管扩张的安全性和长期疗效。
对连续44例经内镜和/或放射学检查发现有症状的沙茨基氏环患者进行研究。在无荧光透视引导下,门诊使用萨瓦里扩张器进行单疗程分级食管扩张。在通过食管测压和24小时动态pH监测进行适当评估后,确诊为胃食管反流病(GERD)的患者持续接受奥美拉唑治疗。前瞻性记录所有结果,包括临床随访和探条扩张术的技术方面。在内镜检查和/或放射学记录环的情况后再次扩张的必要性被视为环的复发。
4例(9%)患者需要进行第二个疗程以确保症状完全缓解。2例(4.5%)患者扩张后发生菌血症,作为门诊患者接受抗生素治疗。有GERD(n = 14)和无GERD(n = 30)的患者在性别、年龄、体重指数、吸烟和饮酒情况、环水平处食管腔直径、静息下食管括约肌压力、吞咽困难持续时间、随访期间服用抗酸剂的需求以及随访持续时间方面具有可比性。GERD患者在平均43.8±9.3个月(范围27 - 62个月)的随访期内未出现环的复发;然而,无GERD患者在平均40.6±12.2个月(范围10 - 58个月)的随访期内,32%的患者在平均19.9±10.6个月后复发(P = 0.04)。
在无荧光透视引导下,使用大口径萨瓦里扩张器进行单疗程分级食管扩张可安全用于缓解食管下段(沙茨基氏)环患者的症状。如果存在GERD,应进行治疗以防止环的症状复发。