Penna Maria L F, Penna Gerson O
Instituto de Medicina Social, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Trop Med Int Health. 2007 May;12(5):647-50. doi: 10.1111/j.1365-3156.2007.01837.x.
Only six countries did not meet the leprosy elimination target during 2005, amongst them Brazil. In 2006, the Brazilian Ministry of Health announced a reduction of the detection rate of 24% or 10 900 cases from 2004 to 2005. A negative binomial parabolic regression model was adjusted to the detection rate historical series from 1980 to 2004, in order to predict the 2005 detection rate and its 95% confidence interval. This analysis showed that the number of new leprosy cases for 2005 could not be predicted from the previous behaviour of the data what calls for an epidemiological or operational explanation hypothesis. The hypothesis that this drop in detected case number is due to operational change, as a reduction in diagnosis or a modification in the reporting routine, is more likely. Recent change in prevalence case definition turned the prevalence ratio a function of only one variable, the detection rate, as the duration of the diagnosed disease became fixed. In the early nineties, based on epidemiological data evaluation, the BMoH recognized the impossibility of reaching the elimination goal, but it committed to seek leprosy control. This position changed after some years. Leprosy Elimination is a strategy supported by the national and international public opinion. As a one for all recipe, it may cause unwanted effects for it is not flexible enough to deal with different epidemiological behaviours and public health traditions.
2005年,只有六个国家未达到麻风病消除目标,巴西是其中之一。2006年,巴西卫生部宣布,2004年至2005年期间,麻风病检出率下降了24%,即减少了10900例。为了预测2005年的检出率及其95%置信区间,对1980年至2004年的检出率历史序列进行了负二项式抛物线回归模型调整。该分析表明,无法根据数据的先前趋势预测2005年新麻风病病例数,这需要一个流行病学或操作方面的解释假设。更有可能的假设是,检出病例数的下降是由于操作上的变化,如诊断减少或报告程序改变。最近患病率病例定义的变化使患病率比值仅成为一个变量(检出率)的函数,因为确诊疾病的持续时间已固定。在九十年代初,基于流行病学数据评估,巴西卫生部认识到无法实现消除目标,但仍致力于寻求麻风病控制措施。几年后,这一立场发生了变化。消除麻风病是一项得到国内和国际舆论支持的战略。作为一种一刀切的方案,它可能会产生不良影响,因为它不够灵活,无法应对不同的流行病学行为和公共卫生传统。