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阵发性心房颤动射频导管消融术后左心房大小及功能

[Left atrial size and function after radiofrequency catheter ablation for paroxysmal atrial fibrillation].

作者信息

Wu Shu-lin, Liao Hong-tao, Fei Hong-wen, Yang Ping-zhen, Zhan Xian-zhang, Xue Yu-mei

机构信息

Department of Cardiology, Guangdong Provincial People's Hospital, Guangzhou 510100, China.

出版信息

Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Feb;35(2):127-31.

Abstract

OBJECTIVE

To evaluate the impact of radiofrequency catheter ablation on left atrial (LA) size and function in patients with paroxysmal atrial fibrillation (PAF) and whether there is any difference between segmental pulmonary vein ostial isolation (SPVI) and circumferential pulmonary vein ablation (CPVA).

METHODS

Sixty-six patients with highly symptomatic atrial fibrillation were assigned to undergo either SPVI or CPVA. Transthorax echocardiography was performed before, 1 day, 1 months and 3 months after the procedure. LA dimension, LA area, late diastolic peak velocity of mitral valve inflow (A) and peak atrial systolic mitral annulus velocity (A') were recorded.

RESULTS

Of 66 consecutive patients with symptomatic PAF, 30 patients underwent SPVI and 36 underwent CPVA. After a mean follow-up of (315 +/- 153) days, 21 patients (70%) after SPVI and 28 patients (75%) after CPVA were free of atrial tachyarrhythmia. As compared with the baseline, LA area decreased at 1-month after ablation in SPVI group and at 3-month in CPVA group. LA dimension decreased also in SPVI group, but did not in CPVA group. A velocity and A' velocity declined remarkably 1 day after CPVA, and restored 3 months later. The former went back to the level of baseline, and the latter exceeded it apparently. In SPVI group, A velocity increased at 1-month, and maintained in 3-month after ablation. A' velocity increased at 3-month after ablation. No reduction of A velocity or A' velocity was found after SPVI.

CONCLUSIONS

This study demonstrated a decrease in LA area and an improvement in LA systolic function 3 months after ablation for PAF. The LA damage by CPVA was more than that by SPVI, which was characterized by the reduction of LA function 1 day after procedure and the delayed improvement of LA size and functional parameters.

摘要

目的

评估射频导管消融对阵发性心房颤动(PAF)患者左心房(LA)大小和功能的影响,以及节段性肺静脉口部隔离(SPVI)与环肺静脉消融(CPVA)之间是否存在差异。

方法

66例症状严重的心房颤动患者被分配接受SPVI或CPVA。在手术前、术后1天、1个月和3个月进行经胸超声心动图检查。记录LA维度、LA面积、二尖瓣流入道舒张晚期峰值速度(A)和心房收缩期二尖瓣环峰值速度(A')。

结果

在66例有症状的PAF连续患者中,30例接受了SPVI,36例接受了CPVA。平均随访(315±153)天后,SPVI组21例患者(70%)和CPVA组28例患者(75%)无房性快速心律失常。与基线相比,SPVI组消融后1个月LA面积减小,CPVA组消融后3个月LA面积减小。SPVI组LA维度也减小,但CPVA组未减小。CPVA术后1天A速度和A'速度显著下降,并在3个月后恢复。前者恢复到基线水平,后者明显超过基线水平。在SPVI组,消融后1个月A速度增加,并在3个月时维持。消融后3个月A'速度增加。SPVI术后未发现A速度或A'速度降低。

结论

本研究表明,PAF消融术后3个月LA面积减小,LA收缩功能改善。CPVA对LA的损伤大于SPVI,其特征是术后1天LA功能降低,LA大小和功能参数改善延迟。

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