Grifo J, Talebian S, Keegan D, Krey L, Adler A, Berkeley A
Division of Reproductive Endocrinology and Infertility, New York University School of Medicine, New York, New York, USA.
Fertil Steril. 2007 Oct;88(4):978-81. doi: 10.1016/j.fertnstert.2006.12.012. Epub 2007 Apr 18.
We describe our experience of over 300 cycles of preimplantation genetic diagnosis (PGD) and report clinical pregnancy rates (35%-67%) that support using this technology to screen for genetic disorders and chromosomal abnormalities. In clinical practice for over ten years, PGD offers couples the earliest form of genetic screening and may help improve ongoing pregnancy rates in poor-prognosis patients.
我们描述了超过300个植入前基因诊断（PGD）周期的经验，并报告了临床妊娠率（35%-67%），这些数据支持使用该技术筛查基因疾病和染色体异常。在超过十年的临床实践中，PGD为夫妇提供了最早形式的基因筛查，并可能有助于提高预后不良患者的持续妊娠率。
