Hu Houchun H, Campeau Norbert G, Huston John, Kruger David G, Haider Clifton R, Riederer Stephen J
Magnetic Resonance Laboratory, Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA.
Radiology. 2007 Jun;243(3):853-61. doi: 10.1148/radiol.2433060819. Epub 2007 Apr 19.
Informed consent was obtained; the study was HIPAA compliant and institutional review board approved. Fourfold accelerated (FFA) two-dimensional (2D) sensitivity encoding (SENSE) (65 seconds) was prospectively compared with its nonaccelerated counterpart (4 minutes 20 seconds) for diagnostic image quality and sharpness of visualization of blood vessels at 1.5 T with three-dimensional (3D) intracranial contrast-enhanced magnetic resonance venography in 18 consecutive volunteers (10 men, eight women; mean age, 48.4 years) and two patients (55-year-old man, 30-year-old woman). Two readers compared FFA 2D SENSE results with results from its nonaccelerated counterpart; they rated visualization of large and medium sinuses as equivalent (P>.1) and that of small deep cerebral veins (P<.01) and superficial cerebral veins (P<.001) as superior. Overall diagnostic image quality ratings were excellent for 62% and 80% of nonaccelerated and FFA 2D SENSE results, respectively (P<.05). FFA 2D SENSE may become the method of choice for fast visualization of intracranial venous vasculature in clinical practice.
已获得知情同意；该研究符合健康保险流通与责任法案（HIPAA）要求，并经机构审查委员会批准。在1.5T磁场下，对18名连续志愿者（10名男性，8名女性；平均年龄48.4岁）和两名患者（55岁男性，30岁女性）进行三维颅内对比增强磁共振静脉血管造影时，前瞻性地比较了四倍加速（FFA）二维（2D）敏感性编码（SENSE）（65秒）与其非加速对应序列（4分20秒）的诊断图像质量和血管可视化清晰度。两名阅片者将FFA 2D SENSE结果与其非加速对应序列的结果进行比较；他们将大、中静脉窦的可视化评为等效（P>0.1），而将小的脑深部静脉（P<0.01）和脑浅表静脉（P<0.001）的可视化评为更优。总体诊断图像质量评分中，非加速序列和FFA 2D SENSE结果分别有62%和80%为优秀（P<0.05）。FFA 2D SENSE可能会成为临床实践中快速可视化颅内静脉血管系统的首选方法。
