Fajardo Carmona A V, Pascual Castroviejo I
An Esp Pediatr. 1975 Nov-Dec;8(6):639-50.
13 cases of ACS are presented: seven of them were identified as Apert's syndrome; two as Chotzen's syndrome; three as Carpenter's syndrome, and one as Pfeiffer's syndrome. These disorders have no known ethiology. However, it is necessary to look for diabetic antecedents and dermatogliphus alterations, both in the patient and the parents. An attempt to give an explanation of their hereditary penetrance is made. Frequency of associated abnormalities, mental retardation, therapeutics, prognosis, and recent encouraging results of plastic surgery of the face are reviewed.
本文报告了13例尖头并指（趾）综合征（ACS）病例：其中7例被诊断为Apert综合征；2例为Crouzon综合征；3例为Carpenter综合征，1例为Pfeiffer综合征。这些病症的病因尚不清楚。然而，有必要在患者及其父母中寻找糖尿病病史和皮纹改变。本文尝试对其遗传外显率作出解释。同时回顾了相关异常、智力发育迟缓、治疗方法、预后情况，以及近期面部整形手术取得的鼓舞人心的成果。
