Braunschweig Frieder
Department of Cardiology, Karolinska University Hospital, 171 76, Stockholm, Sweden.
Heart Fail Rev. 2007 Jun;12(2):157-66. doi: 10.1007/s10741-007-9019-0.
Electrical devices, Cardiac Resynchronization Therapy (CRT) pacemakers, the Implantable Cardiac Defibrillator (ICD) and a combination of both, constitute an important line of treatment in the therapy of moderate to severe chronic heart failure. The effectiveness of these devices in the treatment of acute decompensated heart failure has yet to be systematically evaluated. However, the beneficial clinical effects of CRT translate into a marked reduction of heart failure-related hospitalization. Devices also offer unique diagnostic applications by continuous measurement of clinically useful physiological parameters over time. Of particular interest, monitoring of intrathoracic impedance and right ventricular pressures allows to detect changes in volume load in an early stage prior to the development of clinical symptoms. This information could be helpful to stop further progression to acute cardiac decompensation and to avoid hospitalization and acute clinical events. Using modern telecommunication technology, patients can also be remotely monitored in their daily living environment. In consequence, the incorporation of device technology into heart failure management programs calls for a close cooperation between heart failure specialists and electrophysiologists. This review addresses therapeutic and diagnostic aspects of device therapies in the context of acute heart failure.
电气设备、心脏再同步治疗(CRT)起搏器、植入式心脏除颤器(ICD)以及两者的组合,构成了中重度慢性心力衰竭治疗中的重要治疗手段。这些设备在急性失代偿性心力衰竭治疗中的有效性尚未得到系统评估。然而,CRT的有益临床效果可显著减少与心力衰竭相关的住院次数。设备还通过持续测量一段时间内临床上有用的生理参数提供独特的诊断应用。特别值得关注的是,监测胸内阻抗和右心室压力能够在临床症状出现之前的早期阶段检测到容量负荷的变化。这些信息有助于阻止病情进一步发展为急性心脏失代偿,并避免住院和急性临床事件。利用现代电信技术,还可以在患者的日常生活环境中对其进行远程监测。因此,将设备技术纳入心力衰竭管理计划需要心力衰竭专科医生和电生理学家密切合作。本综述探讨了急性心力衰竭背景下设备治疗的治疗和诊断方面。