Nakata T, Gotoh M, Yonekura S, Tanaka S, Shimamoto K, Kubota M, Tsuda T, Iimura O
Second Department of Internal Medicine and Department of Radiology, Sapporo Medical College, Japan.
J Nucl Med. 1991 Dec;32(12):2291-4.
Indium-111-antimyosin Fab scan was performed in patients with hypertrophic and postpartum cardiomyopathies to assess whether or not myocardial damage can be delineated. In two patients with hypertrophic cardiomyopathy, intense and diffuse antimyosin uptake was observed, although there was no evidence of acute myocardial damage or wall motion abnormality. A patient with postpartum cardiomyopathy showed a dense and relatively localized accumulation in the left ventricular anterior wall in association with thallium perfusion and wall motion abnormalities. Thus, antimyosin scanning can delineate not only manifested but also subclinical myocardial damage in hypertrophic and postpartum cardiomyopathies which may not be detectable by other techniques.
对肥厚型心肌病和产后心肌病患者进行了铟-111抗肌凝蛋白Fab扫描，以评估是否能够明确心肌损伤情况。在两名肥厚型心肌病患者中，尽管没有急性心肌损伤或室壁运动异常的证据，但观察到了强烈且弥漫性的抗肌凝蛋白摄取。一名产后心肌病患者在左心室前壁出现了密集且相对局限的积聚，伴有铊灌注和室壁运动异常。因此，抗肌凝蛋白扫描不仅可以明确肥厚型和产后心肌病中已表现出的心肌损伤，还能发现其他技术可能检测不到的亚临床心肌损伤。
