中枢神经系统的单一起源？

A single origin of the central nervous system?

作者信息

Telford Maximilian J

机构信息

Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK.

出版信息

Cell. 2007 Apr 20;129(2):237-9. doi: 10.1016/j.cell.2007.03.035.

DOI:10.1016/j.cell.2007.03.035

PMID:17448982

Abstract

As Denes et al. (2007) reveal in this issue, the expression profile and roles of genes that pattern the nervous system in embryos of chordates and annelids are surprisingly similar. This extraordinary conservation suggests that the patterning mechanism has been inherited largely unchanged from the bilaterian common ancestor and that the central nervous system, although dorsal in fish and ventral in worms, is an ancient characteristic of animals.

摘要

正如德内斯等人（2007年）在本期所揭示的那样，在脊索动物和环节动物胚胎中，构建神经系统模式的基因的表达谱和作用惊人地相似。这种非凡的保守性表明，模式形成机制在很大程度上是从两侧对称动物的共同祖先那里继承而来且基本未变，并且中枢神经系统虽然在鱼类中位于背部，在蠕虫中位于腹部，但却是动物的一个古老特征。