Mc Fleming Jennifer
Institute for Molecular Biosciences, University of Queensland, St Lucia 4072, Brisbane, Queensland, Australia.
Int J Law Psychiatry. 2007 May-Jun;30(3):182-90. doi: 10.1016/j.ijlp.2007.03.002. Epub 2007 Apr 20.
The field of mental health offers a valuable context in which to examine new challenges presented by human genetic research databases to the legal, ethical and regulatory frameworks for human genetic research. Longitudinal prospective genetic research of psychiatric disorders often involves access to human genetic research databases and to stored tissue for future uses that cannot be specified at the time the patient consents to their collection. The potential of such research to contribute to an improved understanding and treatment of complex genetic diseases such as schizophrenia presupposes sound ethical, legal and regulatory frameworks to ensure public trust and preparedness to participate in such research. This article provides a brief overview of some of the ethical and legal challenges posed by human genetic research databases and their implications for how genetic research should be conducted in the field of mental health.
心理健康领域为审视人类基因研究数据库给人类基因研究的法律、伦理和监管框架带来的新挑战提供了一个有价值的背景。对精神疾病的纵向前瞻性基因研究通常涉及访问人类基因研究数据库和存储的组织以供未来使用，而这些用途在患者同意收集时无法明确指定。此类研究对于增进对诸如精神分裂症等复杂基因疾病的理解和治疗的潜力，预先假定了健全的伦理、法律和监管框架，以确保公众信任并愿意参与此类研究。本文简要概述了人类基因研究数据库带来的一些伦理和法律挑战及其对心理健康领域基因研究应如何开展的影响。
