Lung Teofil, Tăşcău Oana Cristina, Almăşan Horea Artimoniu, Mureşan Ovidiu
Department of Oral and Maxillofacial Surgery, University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania.
J Craniomaxillofac Surg. 2007 Mar;35(2):120-5. doi: 10.1016/j.jcms.2007.02.001. Epub 2007 Apr 20.
Studies prior to 1990 showed an incidence of 5% for oral and maxillofacial cancer in Romania. In this paper (Part 1) an evaluation of malignant tumour cases, covering a 10-year period is made regarding histological forms, the relationships of malignant tumours to patients' geographic origin, environment, age, gender of patients and lymph node involvement.
From 1485 patients with malignant oral and maxillofacial tumours, 1072 cases fulfilled the criteria for inclusion in this study. The following data were examined: patients' charts and medical records as well as pathology reports.
From 16,315 patients admitted to this hospital between 1993 and 2002, 9% presented with primary ('de novo') malignant tumours; 2/3 were male patients; average age at presentation was 61 years for males and 59 years for females; 47% presented with stage IV tumours; out of the 'de novo' tumours, 93% were carcinomas and 4% sarcomas; 56% of patients had positive lymph nodes at presentation.
The number of head and neck cancer cases increased in the last 15 years; almost half of the patients presented with tumours in stage IV.
1990年以前的研究表明,罗马尼亚口腔颌面癌的发病率为5%。在本文(第一部分)中,对10年间的恶性肿瘤病例进行了评估,内容涉及组织学类型、恶性肿瘤与患者地理来源、环境、年龄、性别以及淋巴结受累情况之间的关系。
在1485例口腔颌面恶性肿瘤患者中,1072例符合本研究的纳入标准。检查了以下数据:患者的病历和医疗记录以及病理报告。
在1993年至2002年间入住本院的16315例患者中,9%患有原发性(“新发”)恶性肿瘤;其中2/3为男性患者;男性患者的平均就诊年龄为61岁,女性为59岁;47%的患者就诊时为IV期肿瘤;在“新发”肿瘤中,93%为癌,4%为肉瘤;56%的患者就诊时淋巴结阳性。
在过去15年中,头颈癌病例数有所增加;几乎一半的患者就诊时肿瘤处于IV期。