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直接血管成形术治疗的ST段抬高型心肌梗死患者术后单导联ST段偏移与长期死亡率

Postprocedural single-lead ST-segment deviation and long-term mortality in patients with ST-segment elevation myocardial infarction treated by primary angioplasty.

作者信息

De Luca G, Suryapranata H, Ottervanger J P, Hoorntje J C A, Gosselink A T M, Dambrink J-H, de Boer M-J, van't Hof A W J

机构信息

Division of Cardiology, Ospedale Maggiore della Caritè, Universitè del Piemonte Orientale A Avogadro, Novara, Italy.

出版信息

Heart. 2008 Jan;94(1):44-7. doi: 10.1136/hrt.2006.103556. Epub 2007 Apr 20.

Abstract

OBJECTIVE

To evaluate the prognostic role of postprocedural single-lead residual ST-segment deviation for electrocardiographic evaluation of myocardial perfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary angioplasty.

DESIGN

Prospective observational clinical cohort study.

SETTING

Tertiary referral centre.

PATIENTS

1660 patients treated with primary angioplasty for STEMI.

MAIN OUTCOME MEASURE

Mortality at 1-year follow-up.

RESULTS

Single-lead ST-segment deviation significantly correlated with infarct size, predischarge ejection fraction, distal embolisation and myocardial blush grade 3. At 1-year follow-up, 63 patients had died. The method correlated well with 1-year mortality. At multivariate analysis, after correction for baseline demographic, clinical and angiographic variables, postprocedural single-lead ST-segment deviation showed better accuracy than residual single-lead ST-segment elevation or resolution and residual 12-lead ST-segment deviation.

CONCLUSIONS

This study showed that maximal residual ST-segment deviation in a single lead at 3 hours after the procedure is an easy and accurate predictor of 1-year mortality after primary angioplasty for STEMI.

摘要

目的

评估在接受直接血管成形术治疗的ST段抬高型心肌梗死(STEMI)患者中,术后单导联残余ST段偏移对心肌灌注心电图评估的预后作用。

设计

前瞻性观察性临床队列研究。

地点

三级转诊中心。

患者

1660例接受直接血管成形术治疗的STEMI患者。

主要观察指标

1年随访期内的死亡率。

结果

单导联ST段偏移与梗死面积、出院前射血分数、远端栓塞及心肌灌注分级3级显著相关。在1年随访期内,63例患者死亡。该方法与1年死亡率相关性良好。在多变量分析中,校正基线人口统计学、临床及血管造影变量后,术后单导联ST段偏移比残余单导联ST段抬高或回落以及残余12导联ST段偏移具有更高的准确性。

结论

本研究表明,术后3小时单导联最大残余ST段偏移是STEMI直接血管成形术后1年死亡率的简便且准确的预测指标。

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