De Luca G, Suryapranata H, Ottervanger J P, Hoorntje J C A, Gosselink A T M, Dambrink J-H, de Boer M-J, van't Hof A W J
Division of Cardiology, Ospedale Maggiore della Caritè, Universitè del Piemonte Orientale A Avogadro, Novara, Italy.
Heart. 2008 Jan;94(1):44-7. doi: 10.1136/hrt.2006.103556. Epub 2007 Apr 20.
To evaluate the prognostic role of postprocedural single-lead residual ST-segment deviation for electrocardiographic evaluation of myocardial perfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary angioplasty.
Prospective observational clinical cohort study.
Tertiary referral centre.
1660 patients treated with primary angioplasty for STEMI.
Mortality at 1-year follow-up.
Single-lead ST-segment deviation significantly correlated with infarct size, predischarge ejection fraction, distal embolisation and myocardial blush grade 3. At 1-year follow-up, 63 patients had died. The method correlated well with 1-year mortality. At multivariate analysis, after correction for baseline demographic, clinical and angiographic variables, postprocedural single-lead ST-segment deviation showed better accuracy than residual single-lead ST-segment elevation or resolution and residual 12-lead ST-segment deviation.
This study showed that maximal residual ST-segment deviation in a single lead at 3 hours after the procedure is an easy and accurate predictor of 1-year mortality after primary angioplasty for STEMI.
评估在接受直接血管成形术治疗的ST段抬高型心肌梗死(STEMI)患者中,术后单导联残余ST段偏移对心肌灌注心电图评估的预后作用。
前瞻性观察性临床队列研究。
三级转诊中心。
1660例接受直接血管成形术治疗的STEMI患者。
1年随访期内的死亡率。
单导联ST段偏移与梗死面积、出院前射血分数、远端栓塞及心肌灌注分级3级显著相关。在1年随访期内,63例患者死亡。该方法与1年死亡率相关性良好。在多变量分析中,校正基线人口统计学、临床及血管造影变量后,术后单导联ST段偏移比残余单导联ST段抬高或回落以及残余12导联ST段偏移具有更高的准确性。
本研究表明,术后3小时单导联最大残余ST段偏移是STEMI直接血管成形术后1年死亡率的简便且准确的预测指标。