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幼年和成年骆驼(单峰驼)组织中的抗氧化剂水平。

Antioxidant levels in tissues of young and adult camels (Camelus dromedarius).

作者信息

Mousa H M, Omer O H, Ali B H, Al-Wabel N, Ahmed S M

机构信息

Department of Food Science and Human Nutrition, Gassim University, P.O. Box. 1482, Buraydah, Al-Gassim 81999, Saudi Arabia.

出版信息

J Physiol Biochem. 2006 Sep;62(3):213-8. doi: 10.1007/BF03168471.

Abstract

In this study, we measured the concentration of some antioxidant substances in erythrocytes hemolysate, liver, kidney and brain in young and adult camels. It has been found that the activity of the antioxidant enzymes glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD) and the concentration of glutathione, ascorbic acid and alpha-tocopherol are high in both young and adult camels. GSH-Px and CAT activities were higher in adult camels than in the young whereas no significant difference in the activity of SOD between young and adult camels was noticed. Glutathione was present in all tissues studied. Ascorbic acid was found to have significantly higher values in young camels. From this study it could be concluded that, as in other mammals, camel tissues contain a powerful antioxidant system. The liver has the highest contents of antioxidants and antioxidant enzymes indicating that it plays an important role in pro-oxidants detoxification. Age has a variable effect on the antioxidant system in camels.

摘要

在本研究中,我们测定了幼年和成年骆驼红细胞溶血产物、肝脏、肾脏及大脑中某些抗氧化物质的浓度。研究发现,幼年和成年骆驼体内抗氧化酶谷胱甘肽过氧化物酶(GSH-Px)、过氧化氢酶(CAT)、超氧化物歧化酶(SOD)的活性以及谷胱甘肽、抗坏血酸和α-生育酚的浓度均较高。成年骆驼体内GSH-Px和CAT的活性高于幼年骆驼,而幼年和成年骆驼体内SOD的活性未观察到显著差异。在所研究的所有组织中均存在谷胱甘肽。发现幼年骆驼体内抗坏血酸的值显著更高。从本研究可以得出结论,与其他哺乳动物一样,骆驼组织含有强大的抗氧化系统。肝脏中抗氧化剂和抗氧化酶的含量最高,表明其在清除前氧化剂方面发挥着重要作用。年龄对骆驼的抗氧化系统有不同的影响。

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