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被误诊为肾细胞癌的肾周软组织炎性肌纤维母细胞瘤。

Inflammatory myofibroblastic tumor of the perirenal soft tissue misdiagnosed as renal cell carcinoma.

作者信息

Bektas Sibel, Okulu Emrah, Kayigil Onder, Ertoy Baydar Dilek

机构信息

Department of Pathology, Hacettepe University Hospital, Ankara, Turkey.

出版信息

Pathol Res Pract. 2007;203(6):461-5. doi: 10.1016/j.prp.2007.02.002. Epub 2007 Apr 23.

Abstract

Inflammatory myofibroblastic tumor (IMT) of the kidney or perirenal soft tissue is a rare benign lesion that can mimic a malignant renal neoplasm. We describe the case of a 51-year-old woman that had originally been misdiagnosed as renal cell carcinoma in another hospital. Histologic re-evaluation of the tumor in our institution showed that it was in fact an IMT. Awareness of this entity is required for rendering the accurate diagnosis. An association with inflammatory infiltrate, frequent erythrocyte extravasations, edematous or myxoid stroma, absence of atypical mitosis, and the results of a detailed immunohistochemical panel might help in the differential diagnosis. Our patient is recurrence-free in the 18th month of post-operative follow-up.

摘要

肾脏或肾周软组织的炎性肌纤维母细胞瘤(IMT)是一种罕见的良性病变,可酷似恶性肾肿瘤。我们描述了一名51岁女性的病例,该患者最初在另一家医院被误诊为肾细胞癌。我们机构对该肿瘤进行的组织学重新评估显示,它实际上是一个IMT。要做出准确诊断,需要了解这个实体。伴有炎性浸润、频繁红细胞外渗、水肿或黏液样间质、无非典型有丝分裂以及详细免疫组化结果可能有助于鉴别诊断。我们的患者在术后随访的第18个月无复发。

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