Orssaud C, Roche O, El Dirani H, Allali J, Dufier J-L
Assistance publique-Hôpitaux de Paris, hôpital européen Georges-Pompidou, consultation d'ophtalmologie, 20, rue Leblanc, 75015 Paris, France.
Arch Pediatr. 2007 Aug;14(8):996-9. doi: 10.1016/j.arcped.2007.03.018. Epub 2007 Apr 23.
In children with painful ophthalmoplegia, the diagnosis of Tolosa-Hunt syndrome or of ophthalmoplegic migraine should only be considered when tumoral, infectious, inflammatory or vascular causes have been excluded by appropriate investigations. Both entities are classified as "neuralgia" by the International Headache Society, and seem to share a similar pathogenic mechanism. Both diseases have many clinical similarities with slight differences concerning pain characteristics or ocular associated symptoms. High resolution CT scan or contrast enhanced MRI can be necessary to exclude other causes of painful ophthalmoplegia. They can sometimes objectify an inflammatory process of the cavernous sinus in Tolosa-Hunt syndrome or a reversible enhancement and thickening of the cisternal segment of the oculomotor nerve during an ophthalmoplegic migraine. Pain and ophthalmoplegia quickly resolve with corticosteroids. Such treatment may decrease the risk of recurrence. It is important to follow-up these patients for a 2 years period and to repeat the etiologic assessment. We report here 2 cases of children with painful ophtalmoplegia.
对于患有疼痛性眼肌麻痹的儿童,只有在通过适当检查排除肿瘤、感染、炎症或血管性病因后,才应考虑诊断为托洛萨-亨特综合征或眼肌麻痹性偏头痛。这两种疾病在国际头痛协会的分类中均属于“神经痛”,且似乎具有相似的致病机制。这两种疾病在临床上有许多相似之处,只是在疼痛特征或眼部相关症状方面存在细微差异。高分辨率CT扫描或增强MRI可能对于排除疼痛性眼肌麻痹的其他病因是必要的。它们有时可以明确托洛萨-亨特综合征中海绵窦的炎症过程,或者在眼肌麻痹性偏头痛期间动眼神经脑池段的可逆性强化和增粗。疼痛和眼肌麻痹使用皮质类固醇后可迅速缓解。这种治疗可能会降低复发风险。对这些患者进行为期2年的随访并重复病因评估很重要。我们在此报告2例患有疼痛性眼肌麻痹的儿童病例。