Lachanas V A, Karatzias G T, Tsitiridis I, Panaras I, Sandris V G
Department of Otolaryngology, General Hospital of Larissa, Larissa, Greece.
J Laryngol Otol. 2008 Jan;122(1):97-9. doi: 10.1017/S0022215106005317.
Tolosa-Hunt syndrome is a rare condition of painful ophthalmoplegia combined with ipsilateral ocular motor nerve palsies, caused by non-specific granulomatous inflammation in the cavernous sinus, superior orbital fissure or orbit. A case of Tolosa-Hunt syndrome misdiagnosed as sinusitis orbital complication is reported.
A patient suffering from left periorbital pain, upper eyelid oedema and ptosis, and horizontal diplopia, diagnosed as sinusitis orbital complication, was referred to our department. Clinical evaluation revealed only a left VIth nerve paresis. Haematological studies, cerebrospinal fluid tests and computed tomography scanning were negative. A magnetic resonance imaging (MRI) scan showed enhancement of the left cavernous sinus. Corticosteroid therapy was commenced, and within three days all symptoms disappeared. A diagnosis of Tolosa-Hunt syndrome was made. Follow-up MRI studies were normal.
Tolosa-Hunt syndrome, although rare, is a nosological entity that otolaryngologists must bear in mind. Magnetic resonance imaging studies are essential in the diagnosis and follow up of these patients, in order to avoid a mistaken Tolosa-Hunt syndrome diagnosis.
托洛萨-亨特综合征是一种罕见的伴有同侧动眼神经麻痹的疼痛性眼肌麻痹疾病,由海绵窦、眶上裂或眼眶的非特异性肉芽肿性炎症引起。本文报告一例被误诊为鼻窦炎眼眶并发症的托洛萨-亨特综合征病例。
一名因左眶周疼痛、上睑水肿和上睑下垂以及水平复视而被诊断为鼻窦炎眼眶并发症的患者被转诊至我科。临床评估仅发现左侧第六神经麻痹。血液学检查、脑脊液检查和计算机断层扫描均为阴性。磁共振成像(MRI)扫描显示左侧海绵窦强化。开始使用皮质类固醇治疗,三天内所有症状消失。诊断为托洛萨-亨特综合征。后续MRI检查结果正常。
托洛萨-亨特综合征虽然罕见,但却是耳鼻喉科医生必须牢记的一种疾病实体。磁共振成像研究对于这些患者的诊断和随访至关重要,以避免误诊为托洛萨-亨特综合征。