Landau Zohar, Wainstein Julio, Hanukoglu Aaron, Tuval Myriam, Lavie Judith, Glaser Benjamin
Diabetes Unit, E. Wolfson Medical Center, Holon, Israel.
J Pediatr. 2007 May;150(5):553-5. doi: 10.1016/j.jpeds.2007.03.004.
We describe a family in which 3/6 siblings had transient, relapsing neonatal diabetes. The father and another sibling had diabetes diagnosed at 20 and 9 years old, respectively. All affected individuals carried the same KCNJ11 gene mutation. In all, sulfonylurea treatment permitted cessation of insulin treatment, with improved glycemic control.
我们描述了一个家庭，其中6个兄弟姐妹中有3个患有短暂复发性新生儿糖尿病。父亲和另一个兄弟姐妹分别在20岁和9岁时被诊断出患有糖尿病。所有受影响的个体都携带相同的KCNJ11基因突变。总体而言，磺脲类药物治疗使胰岛素治疗得以停止，血糖控制得到改善。
